Retinal Detachment / RD
Simulate retinal detachment (RD) — the separation of the neurosensory
retina from the underlying retinal pigment epithelium (RPE), one of the
most sight-threatening emergencies in ophthalmology. The neurosensory
retina depends on the RPE for metabolic support, outer-segment
phagocytosis, visual cycle retinoid recycling, and choroidal blood supply
diffusion. When subretinal fluid accumulates between the photoreceptor
outer segments and the RPE, this intimate metabolic relationship is
disrupted — photoreceptors lose their blood supply, outer segments
degenerate, and irreversible photoreceptor apoptosis begins within hours
to days depending on the extent and location of detachment.
Rhegmatogenous retinal detachment (RRD) — the most common
type — occurs when a retinal break (horseshoe tear, atrophic hole,
or dialysis) allows liquefied vitreous to pass through the break and
accumulate in the subretinal space. Tractional retinal detachment
(TRD) occurs when proliferative fibrovascular or fibroglial
membranes (proliferative diabetic retinopathy, proliferative
vitreoretinopathy) mechanically pull the retina away from the RPE
without a retinal break. Exudative (serous) retinal detachment
results from transudation of fluid through an intact but dysfunctional
RPE or choroid — seen in Vogt-Koyanagi-Harada disease, central serous
chorioretinopathy, choroidal tumours, and severe pre-eclampsia.
Model curtain-like visual field obstruction, central vision loss
(macula-off vs. macula-on), metamorphopsia, ΔE colour shift,
CIE xy chromaticity, and image simulation.
Retinal detachment colour science simulation by Auric Artisan.