30

Simulate acute macular neuroretinopathy (AMN) — a rare retinal condition caused by ischaemia of the deep retinal capillary plexus (DCP) and outer plexiform / Henle fibre layers, producing characteristic dark wedge-shaped or petal-like paracentral scotomas that point toward fixation. AMN predominantly affects young women within days of a viral or flu-like prodrome, oral contraceptive use, sympathomimetic exposure (epinephrine, pseudoephedrine), hypotension, or contrast dye injection. The lesions appear as reddish-brown petal-shaped areas on fundoscopy and infrared reflectance imaging, and correspond precisely to regions of DCP flow void on OCT angiography (OCT-A) with disruption of the outer plexiform and Henle fibre layers on structural OCT. Model deep capillary plexus ischaemia patterns, paracentral scotoma wedge profiles, and combined outer retinal disruption. Inspect ΔE colour shift, CIE xy chromaticity displacement, and image-level visual field impairment. Advanced retinal vascular imaging and neuro-ophthalmology research tool.

Learn more about Auric Artisan, our mission, and our values.

Base color
AMN pattern model & settings
Severity / scotoma density 50%
Image simulation
Upload JPG/PNG (max 1200 × 1200). See how a scene would appear with AMN-associated paracentral scotomas and reduced central contrast.
Research notes
Acute macular neuroretinopathy (AMN) is a rare retinal condition characterised by sudden onset paracentral scotomas in young, otherwise healthy individuals. The condition was first described by Bos & Deutman in 1975. The hallmark lesion — a deep reddish-brown wedge or petal pointing toward the fovea — corresponds to ischaemia of the deep capillary plexus (DCP) at the level of the outer plexiform layer and Henle fibre layer. OCT angiography (OCT-A) has revolutionised the understanding of AMN by demonstrating flow voids in the DCP at precisely the site of the ophthalmoscopic lesion. On structural OCT, the outer plexiform layer shows hyperreflectivity acutely, followed by thinning on follow-up. The paracentral scotoma is often persistent (months to years) and can be demonstrated by microperimetry. AMN lesions follow the curved Henle fibre trajectory from the paracentral retina to the foveal slope, creating the characteristic petal or cuneiform shape. Most patients retain good central visual acuity but have significant paracentral reading difficulty and metamorphopsia.
Swatches
Normal
HEX: — • RGB: — • xy: —
AMN affected
HEX: — • RGB: — • xy: —
ΔE (CIE76)
—
ΔE (CIEDE2000)
—
Deep preview
Normal
AMN (deep)
Chromaticity (CIE xy)
Scotoma chromaticity shift vector
D65 white point: 0.313, 0.329
Image simulation

AMN simulations approximate deep capillary plexus ischaemia using luminance reduction and colour desaturation in the paracentral scotoma region. sRGB displays cannot replicate the spatial scotoma pattern experienced in AMN — this tool provides a colour-science approximation of reduced paracentral contrast and chromatic shifts for educational and research purposes. ΔE2000 per Sharma et al. (2005). Not for clinical diagnosis — OCT and OCT-A are required for definitive AMN characterisation.

Multi-condition comparison
5
Compare normal, Condition A and Condition B across multiple severities. Image-based comparison shows paracentral scotoma impact on real scenes.