Chloropsia Simulator: Green-Tinted Vision, M-Cone Bias & Research Tool

Base color

Model & settings

Chloropsia model

Green shift severity50%

Perceptual severity curve Multi-pass deep simulation Xanthopsia overlay

Image simulation

Choose image Upload JPG/PNG (max 1200 × 1200). Green-bias simulation rendered next to original.

Research notes

Chloropsia (from Greek chloros = green + opsis = sight) is a form of chromatopsia in which all or part of the visual field acquires a green tint. It is most frequently reported in digitalis (digoxin) toxicity, where the cardiac glycoside inhibits retinal Na⁺/K⁺-ATPase and disrupts photoreceptor ion homeostasis, biasing the spectral response toward M-cone (green) wavelengths. Cannabis (THC) reportedly produces mild transient chloropsia via CB1 receptor modulation of retinal bipolar and amacrine cells. Post-cataract surgery patients may experience brief green adaptation as the visual system recalibrates after removal of the yellow-filtered natural lens. "Spectral green bias" shifts color balance toward 530-545 nm; "contrast lift" increases perceived brightness in green-dominant regions. The Xanthopsia overlay checkbox adds a yellow-green tint reflecting the mixed digitalis chromatopsia frequently reported clinically.

Swatches — Reference vs Chloropsia

Reference

HEX: — • RGB: — • xy: —

Chloropsia Sim

HEX: — • RGB: — • xy: —

ΔE (CIE76)

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ΔE (CIEDE2000)

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Deep preview

Reference

Simulated

Chromaticity (CIE xy)

Green shift axis (toward M-cone dominant locus)

D65 white point: 0.313, 0.329

Image simulation

Simulations operate in linear sRGB for perceptual correctness. ΔE2000 implemented locally. Chloropsia is modeled as an M-cone spectral bias (green channel gain increase, red/blue attenuation) reflecting the retinal Na⁺/K⁺-ATPase disruption hypothesized in digitalis toxicity. Contrast lift mode increases local contrast in the green band. Combined mode applies both green spectral bias and contrast enhancement. The xanthopsia overlay adds a yellow-green tint representing the mixed chromatopsia spectrum of digitalis. For perceptual optics research and design accessibility — not clinical diagnosis.

Multi-condition comparison

Condition A

Condition B

Steps

Compare normal, Condition A and Condition B across multiple severities. If an image is loaded it will be processed into the grid, otherwise color swatches are shown.

Advanced mode

Etiology model

Green gain factor

140%

Duration profile

Etiology notes: Digitalis inhibits the Na⁺/K⁺-ATPase in retinal photoreceptors and RPE, altering the dark current and shifting spectral balance toward M-cone wavelengths (530-545 nm). Cannabis-mediated chloropsia likely involves CB1 receptor modulation of retinal interneurons. Post-surgical chloropsia resolves within hours to days as the visual system adapts chromatically.

Model assumptions & limits

Green bias is implemented as a simple green channel gain with complementary R/B attenuation. Real chloropsia involves complex retinal circuit disruption.
Digitalis chromatopsia often presents as mixed xanthopsia-chloropsia (yellow-green); the xanthopsia overlay checkbox approximates this.
Post-surgical chloropsia duration and intensity depend on pre-existing lens yellowing severity — more brunescent lens removal yields more dramatic spectral shift.
No temporal adaptation modeling — the gradual resolution over hours/days is not represented in the static severity snapshot.