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Model & settings
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Research notes
Ischemic optic neuropathy (ION) results from infarction of the optic
nerve blood supply. Anterior ION (AION) affects the optic disc and nerve head; posterior
ION (PION) affects the retrolaminar optic nerve. NA-AION (non-arteritic) is the most
common — associated with crowded disc anatomy and vascular risk factors. A-AION
(arteritic, giant cell arteritis) requires urgent high-dose corticosteroids to prevent
fellow eye involvement. Altitudinal inferior field loss (inferior altitudinal defect) is
the classic NA-AION perimetry pattern.
Swatches — Reference vs Altitudinal Field Loss
Reference
HEX: — • RGB: — • xy: —
Field Loss Sim
HEX: — • RGB: — • xy: —
ΔE (CIE76)
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ΔE (CIEDE2000)
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Reference
Simulated
Chromaticity (CIE xy)
Achromatic axis (to D65)
Image simulation
Original
Ischemic optic neuropathy simulated
Multi-condition comparison
5
Clinical notes: Inferior altitudinal defect is characteristic of
superior optic disc sector infarction in NA-AION (superior posterior ciliary artery
territory). Superior altitudinal loss indicates inferior disc sector involvement.
Sectoral mode approximates arcuate bundle infarction of variable angular extent.
Gaussian edge models watershed zone ischemia with gradual transition from infarcted
to ischemic penumbra.
Model assumptions & limits
- Altitudinal masking is applied as a horizontal band; real AION field defects follow arcuate (curved) boundaries reflecting nerve fiber layer bundle anatomy.
- Sectoral loss approximates arcuate bundle damage; actual sector shape depends on the regional posterior ciliary artery territory involved.
- Contrast attenuation in combined mode uses uniform reduction; real AION contrast loss varies spatially with degree of ischemia.
- Fellow eye fellow-eye sequential involvement in NA-AION (40% at 5 years) is not modeled.