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Simulate the visual effects of ocular albinism: foveal hypoplasia central blur, iris transillumination with photophobia, and optic nerve fiber misrouting effects. Tune severity and inspect ΔE & chromaticity shift toward the hypopigmentation axis (D65).

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Base color
Model & settings
Severity100%
Image simulation
Upload JPG/PNG (max 1200×1200). Simulated canvas next to original.
Research notes
Ocular albinism (OA1/GPR143) simulation models the three principal visual effects: foveal hypoplasia (reduced central acuity from absent foveal pit), iris transillumination (photophobia from melanin deficiency in RPE and iris), and optic fiber misrouting (chiasmal decussation anomaly causing binocular imbalance and VEP asymmetry).
Swatches — Reference vs Ocular Albinism
Reference
HEX: — • RGB: — • xy: —
Simulated
HEX: — • RGB: — • xy: —
ΔE (CIE76)
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ΔE (CIEDE2000)
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Deep preview
Reference
Simulated
Chromaticity (CIE xy)
Hypopigmentation axis (to D65)
D65 white point: 0.313, 0.329
Image simulation

Simulations operate in linear sRGB for better perceptual correctness. ΔE2000 implemented locally. Use the severity slider to blend from normal vision (0%) to full ocular albinism effect (100%).

Multi-condition comparison
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Compare normal, Condition A and Condition B across multiple severities. If an image is loaded it will be processed into the grid, otherwise color swatches are shown.